The Cannabidiol (CBD) industry is a high growth global investment category expected to reach at least USD$12B by 2024.

Global demand for cannabinoids has skyrocketed due to overwhelming scientific research that validates healing claims for CBD as well as a momentous shift away from traditional western medicine towards more holistic, natural sources of treatment and preventative care. The current supply of CBDs will only satisfy 5% of the global demand by 2020. As the largest global supplier of CBD products and formulations, Blue Sky Biologicals is positioned to capture the massive opportunity and need for organic and sustainably produced CBDs.

  • Current CBD supply projected to meet only 5% of global demand by 2020
  • Global CBD market estimated to reach $12B by 2024
  • Legal sales estimated to reach $3B in the United States by 2019

Cannabidiol (CBD) history & background

There is a long and storied history behind hemp and its relationship to humanity that dates back to as early as 8000BC. Until it was outlawed by the Marihuana Tax Act of 1937, hemp was widely recognized as an important dietary staple since it contains cannabinoids, which were understood to be critical in maintaining optimal health and overall well being. Most people have no idea that they have dormant cannabinoid receptors in their body; and, that without a source of cannabinoids, these receptors are never turned on. The U.S. Pharmacopoeia listed cannabis as the primary medicine for more than 100 different illnesses or diseases prior to 1937.

With such widespread uses, it begs the question why this plant was banned. Essentially, hemp was placed into the same category as its sister plant, marijuana, as part of The Marihuana Tax Act. While marijuana and hemp are both derivatives of Cannabis Sativa, they are very different plants. Although both the marijuana and hemp plants produce cannabinoids, the marijuana plant also produces THC (delta-9 tetrahydrocannabinol), a psychoactive compound responsible for generating a mind-altering “high” when broken down by heat and introduced to the body. By contrast, hemp plants do not produce the psychoactive compound THC, but do produce around 100 other cannabinoids with proven beneficial uses. Changes in legislation that have permitted production and consumption of cannabinoids mean that CBDs are now accessible on a global scale.

At Blue Sky, we breed industrial/agricultural hemp specifically for the purpose of developing whole, pure, and effective Cannabidiols (CBDs) to supplement a healthy lifestyle.

The Prevalence of Hemp before 1937

  • The majority of ship sails were made from hemp up until the late 19th century.
  • The principal base for all fabrics and textiles was hemp until the late 1800’s.
  • The majority of all paper was made from hemp until the late 1800’s.
  • The majority of rope was made from hemp until the 1930’s.
  • The primary base for paints and varnishes was hemp seed oil until end of the 19th century.
  • The primary oil for lighting lamps was hemp oil until the beginning of the 19th century.
  • The U.S. Pharmacopoeia listed cannabis as the primary medicine for more than 100 different illnesses or diseases until 1937.

Cannabidiol (CBD) is the most versatile therapeutic cannabinoid that has been defined to date. The effects of CBD have been studied for its benefit in many diseases or circumstances of depressed health. These include:

• arthritis (rheumatoid disease)
• post-traumatic stress disorder (PTSD)
• epilepsy
• antibiotic- resistant infections
• neurological disease
• diabetes mellitus
• chronic traumatic encephalopathy
• insomnia
• dystonia
• muscle spasms (e.g., multiple sclerosis)

• nausea
• anxiety
• neurodegenerative disease (e.g., Alzheimer’s)
• schizophrenia
• social and anxiety disorders
• acne
• inflammation
• depression
• addiction treatment

At Blue Sky Biologicals, we want to harness the incredible power of CBDs and introduce them globally as an essential component of a healthy lifestyle. We create all-natural, full-spectrum, CBD-rich products that help restore the body’s natural internal balance for optimal health.

How CBDs work to optimize health

One of the most important systems we have internally is our endocannabinoid system, which is involved in a myriad of physiological and psychological processes.When consumed, cannabinoids attach themselves to both CB1 and CB2 receptors.CB1 receptors are found all around the body, but are heavily concentrated in the brain and deal mainly with coordination, movement, pain, emotions, mood, thinking, appetite, and memories. CB2 receptors, commonly organized in the immune system, affect inflammation and pain.

Cannabidiol (CBD) has been shown to act as a substance that initiates a physiological response when combined with a receptor, such as the 5-HT1A, which may account for some of its anxiolytic, antidepressant, and neuroprotective actions. In addition, CBD has been proposed to play an important role in the management of epilepsy(convulsions), inflammation, and nausea. The absence of psychoactive actions of CBD is advantageous in the treatment of diseases, especially in children and the elderly. This circumstance reinforces the potential value of CBD in childhood epilepsy.

Novel proposals for the use of CBD in medical treatment include its potentially beneficial effects on psychosis (schizophrenia), skin disease (acne), and metastatic spread of cancer (notably breast cancer). The neuroprotective effects of CBD are becoming well defined, and much investigation is underway on its anticancer effects. It appears that CBD acts to facilitate apoptosis, and this may be due to potential actions on mutant P53 proteins that are found in cancer cells. It has been suggested that CBD may be as effective as THC in the management of pain or the negative consequences of cancer, such as wasting syndrome.

It has been demonstrated that CBD may reduce symptoms of schizophrenia, perhaps as a result of its ability to stabilize the function of NMDA receptor pathways that interact with norepinephrine and GABA. These favorable effects have been found to be equivalent to those experienced with certain types of schizophrenia drug treatment(e.g., amisulpride). Cannabidiol (CBD) reduces social and anxiety disorders, and it has a role in reducing social isolation that can be induced by THC. Some studies have suggested that CBD is effective in controlling dystonic symptoms, and it may play a role in protecting alcohol-induced neurogenic deterioration due to binge drinking. There are a number of miscellaneous effects of CBD, such as calming effects, the potential of lowering blood sugar in diabetes mellitus individuals, relieving stress, and assisting with sleep deprived individuals.

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